- 作者: Yi-Ting Chen; John T. Kung
- 作者服務機構: Institute of Molecular Biology, Academia S璯ica, 128, 2nd Section, Academy Road, Nankang District, Taipei, 11529, Taiwan
- 中文摘要: --
- 英文摘要: NKT cells, naive CD4+ T cells, and TCR-γδ T cells belong to distinct T cell lineages but all express T cell receptors generated through random combinatorial joining of V-(D)-J genes. These distinct lineage T cells also possess the property of promptly activating the IL-4 gene upon T cell receptor stimulation. A comparative accounting of features as they pertain to IL-4 inducibility in these three distinct lineage T cells is provided here.
- 中文關鍵字: --
- 英文關鍵字: IL-4 inducibility, naive CD4+ T cells, NKT cell, post-thymic regulation, TCR-γ δ T cell, thymus