- 作者: Gon-Ann Lee, Calvin Ping-Kuang Chen and Mei-Yun Chen
- 中文摘要: 8-Bromobicyclo[5.1.0]oct-1(8)-ene (7), an intermediate for the preparation of 8-substituted bicyclo[5.1.0]oct-1(8)-enes, was synthesized by debromination of 1,8,8-tribromobicyclo[5.1.0] octane (6). Compound 7 underwent bromo-lithium exchange followed by nucleophilic substitution reactions to generate bicyclo[5.1.0]oct-1(8)-ene (5), 8-methylbicyclo[5.1.0]oct-1(8)-ene (10), and 8-trimethylsilylbicyclo[5.1.0]oct-1(8)-ene (11). The bicyclic cyclopropenes 7, 5, 10, and 11 reacted with cyclopentadiene to form adducts 12, 13, 14, and 15, respectively. All of these Diels-Alder adducts are endo-exo isomers (endo-addition from the view of the cyclopropene and exo-addition from the view of the cyclooctene).
- 英文摘要: --
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