- 作者: 林雲蓮
- 作者服務機構: National Research Institute of Chinese Medicine, Taipei 112, Taiwan, R.O.C.
- 中文摘要: A new dihydrobenzodioxane derivative, origalignanol (10), together with nine polyphenolic compounds, salvianolic acid A (1), salvianolic acid C (2), lithospermic acid (3), apigenin 7-O-b-D-glucuronide (4), apigenin 7-O-b-D-(62-methyl)glucuronide (5), luteolin, (6), luteolin 7-O-b-D-glucopyranoside (7), luteolin 7-O-b-D-glucuronide (8), and luteolin 7-O-b-D-xylopyranoside (9), were isolated from the aqueous ethanolic extract of the aerial parts of Origanum vulgare for the first time. The structure of new compound 10 was determined on the basis of spectroscopic methods. Compound 5 is probably an artifact formed during the isolation. Compounds 1, 2 and 3 showed strong DPPH radical scavenging activity with an EC50 of 7.2 ± 0.4, 9.6 ± 0.9, and 9.5 ± 0.7 mM, respectively, and protected rat hepatocytes from CCl4-damage at 100 mM.
- 英文摘要: --
- 中文關鍵字: Origanum vulgare; ?Salvianolic acid A; ?Salvianolic acid C; ?Lithospermic acid; ?Flavonoids; ?Origalignanol.
- 英文關鍵字: --