- 作者: 方郁婷,林嘉寧,吳煥婷,李衍彰
- 作者服務機構: Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan, R.O.C.
- 中文摘要: Total synthesis of (±)-glyflavanones and glychalcones was accomplished starting from the known 1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone (6). A new approach to synthesis of flavanones, based on a high yielding N-benzylcinchoninium salt catalyzed chromane ring forming enantioselective cyclization process, is described. Also, synthesis of (+)-glyflavanone 1, the natural enantiomer, was achieved through optical resolution of a key intermediate in racemic synthesis.
- 英文摘要: --
- 中文關鍵字: Enantioselectve; Glyflavanones; N-benzylcinchoninium salt.
- 英文關鍵字: --