- 作者: 王義烽 ; 翁啟惠
- 作者服務機構: Dept. of Chemistry, Texas AM Univ., College Station, Texas, U.S.A.
- 中文摘要: Efficient procedures have been developed for the stereospecific syntheses of platelet-activating factor and its 2-acetamido analog, an inhibitor of phospholipase A/sub 2/. (S)-3-O-Acetyl-2-O-benzylglycerol and(S)-2-N-benzyloxycarbonyl-3-O- valerylserinol are used as starting materials for the synthese. Both chiral synthons are prepared from lipase-catalyzed acetylation and hydrolysis of the corresponding meso precursors.
- 英文摘要: --
- 中文關鍵字: Chemoenzymatic Synthesis; Platelet Activating Factor; Inhibitor
- 英文關鍵字: 抑制劑;化學-酵素合成法;血小板活化因子