• 作者： 施維貞; 約翰柯柏; 謝漢臣
• 作者服務機構： Veterans Affairs Medical Center and University of Kentucky Medical Center
• 中文摘要： 為了以核子醫學方法證實腹膜腔液向著中隔腔的淋巴腺流通，七隻大白鼠構成此研究，每隻以300 - 350uCi放射性銲標化白蛋膠樣物連同5西西生理鹽水注射入腹膜腔，四小時後，以閃爍造影機造影大白鼠的胸腹部。每隻的照片顯示對稱性中隔腔淋巴腺攝取，此乃證明腹膜腔液向著中隔腔淋巴腺流通。此種動物研究模型，可作更進一步的腹腔與中隔腔之閒淋巴液生理病的研究。
• 英文摘要： Lymphatic drainage from the peritoneal cavity to mediastinal lymph nodes has been reported, in-dicating that abdominal fluid is not immobile. We studied this movement in rats receiving Tc-99m albuminnanocolloid which has smaller particle sizes than does Tc-99m microaggregated albumin colloid used forliver/spleen imaging. The Tc-99m albumin nanocolloid had a radiochemical purity of 99.33%-99.77% withfree pertechnetate of 0.23%-0.67%. During pentobarbital anesthesia, thoracoabdominal images were ob-tained 4-6 hr after intraperitoneal injection of 350 mCi Tc-99m albumin nanocolloid with 5 ml of normalsaline. The images showed symmetrical radiotracer localization in the mediastinal lymph nodes. Scintigraphicdemonstration of drainage to the mediastinal region from the peritoneal cavity may be explained by flowdirectly into mediastinum through the lymphatic system, indicating lymphatic patency between the peritonealcavity and mediastinum. Absence of visualization may indicate lymphatic block. This type of informationconcerning lymphatic drainage may have clinical impact for a patient with malignant or intractable ascites.The radionuclide technique is easily performed for this assessment.
• 中文關鍵字： Scintigraphy; mediastinal lymph nodes; peritoneal cavity; Tc-99m albumin nanocolloid
• 英文關鍵字： --