第10卷‧第1期,
198201
, pp. 63-66
尿崩症鼠子宮對催產素敏感性之研究
- 作者：
楊志剛; 謝來安; 楊忠謀; 蔡向榮
- 作者服務機構：
國防醫學院及生物物理學系
- 中文摘要：
利用手術方法，造成大白鼠尿崩症後7～14天，我們試測腦下腺後葉中催產素含量甚微，不
及正常者3%。我們亦測知尿崩症鼠子宮重量與正常鼠子宮重量並無差別，，兩者子宮對催產素之
反應曲線頗為平行，但尿崩症鼠子宮對催產素之敏感性?為正常者之二倍。這種增強現象，可使
利用大白鼠作催產素之生物鑑定有更精密之結果。a
- 英文摘要：
Rats with diabetes insipidus (DI) producedby hypothalamic lesions are approximatelytwice as sensitive as normal rats to theuterotonic action of oxytocin at dose levelsranging from 0.8 to 2.0 milliunits. Since theuterus weight and the maximal active tensionin response to oxytocin in DI rats are notsignificantly different from those in normal rats,it suggests that supersensitivity to oxytocin inDI rats probably results from increases in theconcentration of oxytocin receptors rather thanfrom an alteration of intracellular contractilechanges.
- 中文關鍵字：
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- 英文關鍵字：
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