- 作者: --
- 作者服務機構: Chemistry Department, Faculty of Science, South Valley University, 82524 Sohag, Egypt
- 中文摘要: Condensation of 1-phenylpyrazolidine-3,5-dione 1 with 3-formylchromone afforded 4-(chromenylmethylene)pyrazolidinedione 2, which was reacted with hydrazine or hydroxylamine in different molar ratios and conditions to give the corresponding pyrazole and isoxazole derivatives 3-8, respectively. Compound 2 was subject to react with ammonia, N,S- or S,S-acetals, mercaptoacetic acid, cyanoacetamide or cyanothioacetamide to give the corresponding pyridine, dithiine, thiazine and thiophene, 9-14, respectively. The reaction of compound 2 with thiourea, guanidine, cystamine, o-aminothiophenol, ethylenediamine, o-phenelenediamine or barbituric acid afforded the corresponding thiazine, pyrimidine, thiazepine, diazepine, and pyran derivatives 17-23, respectively. The study of the reaction of compound 2 with nucleophiles via chromene ring opening was investigated.
- 英文摘要: --
- 中文關鍵字: Chromone; Pyrazolidine-3,5-dione; Pyridine; Thiazepine; Diazepine; Michael reaction
- 英文關鍵字: --