- 作者: 王英基、黃耿祥、陳行明、吳仲欽、林國鈞
- 作者服務機構: Faculty of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung City 807, Taiwan, R.O.C.
- 中文摘要: A new and highly efficient method for the conversion of aldoximes to nitriles was established. By fusing with phthalic anhydride, aldoximes were efficiently and smoothly converted into nitriles, in high yields (over 85%) and in a short time (within 5 minutes). The mixture of phthalic anhydride, a cyclic anhydride, and aldoximes in fusing state set up an ideal transition state for a selective [3.3]-sigmatropic rearrangement of the acylated aldoximes to nitriles.
- 英文摘要: --
- 中文關鍵字: Aldoximes; Phthalic anhydride; Nitriles.
- 英文關鍵字: --