- 作者: 閻福林、王愛霞、賈忠建
- 作者服務機構: College of Chemistry and Chemical Engineering, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China
- 中文摘要: Four new benzofuran derivatives were isolated from the roots of Ligularia stenocephala; they were named as ligustenin A (1), B (2), C (3) and D (4), and the structures were established by spectroscopic methods including 2D NMR techniques. Ligustenin A (1) was found to exhibit potent anti-tumor activity against HL-60 (human leukemia cells), Bel-7402 (human hepatoma cells) and HO-8910 (human ovarian neoplasm cells) with IC50 values of 18.6, 27.6 and 57.5 mM, respectively.
- 英文摘要: --
- 中文關鍵字: Ligularia stenocephala; Compositae; Benzofuran derivative.
- 英文關鍵字: --