- 作者: 陳水田; 翁志雄; 王光燦
- 作者服務機構: Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan, R.O.C.
- 中文摘要: o-C lorobenzyloxycarbonylimino-2-phenylacetonitrile (Cl-Z-ON) and .rho.-methoxybenzyloxycarbonyllimino-2-phenylacetonitrile (MOZ-ON) have been prepared from 2-hydroxyimino-2-phenylacetonitrile (oxime), phosgene, and the corresponding alcohols. Cl-Z-on is synthesized for the first time and found to be stable at room temperature. MOZ-ON is utilized for the preparation of MOZ-amino acids under various conditions. The oxime car be recovered and reused. The combination of Cl-Z- and MOZ- for the alternative masking of the N/sup .epsilon./- and N/sup .alpha./-amino groups of lysine residue has also been studied.
- 英文摘要: --
- 中文關鍵字: high purity MOZ-amino acid; MOZ-ON;Cl-Z-ON.
- 英文關鍵字: high purity MOZ-amino acid; MOZ-ON;Cl-Z-ON.