- 作者: 王潤玲, 李文明, 劉甍源, 徐為人
- 作者服務機構: School of Pharmacy, Tianjin Medical University, Tianjin 300070, P. R. China
- 中文摘要: A set of novel imidazolidinedione derivatives were synthesized and evaluated as potential antidiabetic agents. Imidazolidinedione scaffold-based molecules were synthesized and validated on a mice hyperglycemia model caused by alloxan. As a result, three of them showed antihyperglycemic activities. This research provides useful clues for further design and discovery of antidiabetic agents.
- 英文摘要: --
- 中文關鍵字: Diabetes; Antidiabetic agent; Insulin resistance; Imidazolidinedione derivatives.
- 英文關鍵字: --