- 作者: Chun-Yen Chiu, Chao-Nan Kuo, Wen-Fa Kuo and Mou-Yung Yeh*
- 作者服務機構: Department of Chemistry, National Cheng Kung University, Tainan, Taiwan 70101, R.O.C.
- 中文摘要: In addition to pyridines, a-chloroformylarylhydrazine hydrochloride 1 can also react with some N-heterocyclic compounds. The cycloaddition of 1 with isoquinoline was achieved to obtain 3. The production of 4, 5, 6 given by cycloaddition of 1 with pyridazine was dependent on the reaction condition. Some heterocyclic compounds bearing an X-C=N (X:S, N) group on the ring can react with 1 to gain the derivatives of 2,4-dihydro-1,2,4-triazol-3-one. 7, 8, 9 and 10 were given by reaction of 1 with 1,3,5-triazine, 1,4,5,6-tetrahydropyrimidine, 1,3-thiazole and 2-amino-1,3-thiazole, respectively. The reactions for 2-amino-1,3,4-thiadiazole and 3-amino-1,2,4-triazole had the same product 11.
- 英文摘要: --
- 中文關鍵字: a-Chloroformylarylhydrazine hydrochloride; Pyridines; 2-Aryl-2H-[1,2,4]triazolo[4,3-a]pyridin-3-ones; Cycloaddition; N-heterocyclic compounds; Isoquinoline; Pyridazine; 1,3,5-Triazine; 1,4,5,6-Tetrahydropyrimidi; …
- 英文關鍵字: a-Chloroformylarylhydrazine hydrochloride; Pyridines; 2-Aryl-2H-[1,2,4]triazolo[4,3-a]pyridin-3-ones; Cycloaddition; N-heterocyclic compounds; Isoquinoline; Pyridazine; 1,3,5-Triazine; 1,4,5,6-Tetrahydropyrimidi; …