• 作者： 徐惠美；方懷時
• 作者服務機構： 國立臺灣大學醫學院生理學科
• 中文摘要： 以低壓室飛行之各種高度表示缺氧之程度，高度愈高，表示缺氧愈嚴重。以骨炭粉標記法測定小腸之推進動作，骨炭粉 在小腸內推進距離之百分率愈高，表示其推進動作愈?。食物之質正常，但不使大白鼠?日獲得足?量之食物共達十五星 期，使其遭受長期之半禁食，致體重減半。 實驗之結果探悉（甲）18,000呎之高度，並不影響大白鼠之小腸推進動作。（乙）使高度增至22,000呎，可使小腸推進 動作減弱。其缺氧閾在18,000?22，000呎之高度。（丙）長期之半禁食，可使小腸之組織萎縮（小腸之重量減輕），且小腸之 推進動作變慢。聯合（乙）及（丙）二者所導致小腸推進動作之滅弱程度與（丙）單獨所引起小腸推進動作之減弱程度相似 ，顯示長期半禁食可使大白鼠對於缺氧之抵抗力增?。如以小腸推進動作?指標，測知遭受長期半禁食之大白鼠，其缺氧閾 在22,000?26,000呎之高度。
• 英文摘要： The effect of hypoxia and prolonged semi-starvation on the propulsive motility of the small intestine of the anesthetized male rats was studied by means of the charcoal-marker method. Hypoxia did not affect the intestinal propulsive motility significantly at a simulated altitude of 18,000 feet. Above this level, the motility was significantly decreased by the hypoxia. The threshold for such anesthetized rats lay between 18,000 and 22,000 feet. If the rats were semi-starved for 15 weeks, there was a significant decrease in intestinal propulsive motility. The reduction in intestinal motility from the combined action of hypoxia (22,000 feet) and semi-starvation was no greater than that from semi-starvation alone. The finding thus suggested an increased resistance to hypoxia caused by prolonged semi-starvation. This resistance to hypoxia, however, was not shown when the rats were subjected to a simulated altitude of 26,000 feet. The threshold for hypoxia on the intestinal propulsive motility in prolonged semi-starved rats lay somewhere between 22,000 and 26,000 feet.
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