• 作者： 潘以宏; 林清淵; 薦田溫子; 今井淨子; 日沼賴夫
• 作者服務機構： 國立臺灣大學醫學院細菌學科; 榮民總醫院小兒科; 日本京都大學病毒研究所
• 中文摘要： 日本九州之長崎、鹿兒島及琉球群島為已知之成人T細胞白血病病毒流行地帶之一，臺灣地處這些地區的南端，自古以來即有相當頻繁的交流，因此本篇乃進行臺灣地區血清流行病學之研究，利用明膠凝集法及間接螢光抗體法測定anti-ATLV價。結果顯示anti-ATLV陽性者零星地出現於本省之花蓮、臺中、南投及基隆等縣市，各縣市的陽性率由0到5.6％（ATL病患家族除外）。同時檢驗本省947名山胞之血清，沒有發現陽性者存在。在受檢之3682名平地居民（漢民族）中，共有39名陽性者，全省（山胞除外）anti-ATLV的陽性率約為1.0％，由此估計臺灣地區約有80,000人為anti-ATLV陽性。另外，追綜陽性者之家屬，發現夫婦均為陽性之比率最高，夫婦之一為陽性亦有；還有陽性子女得自陽性母親。用免疫沈澱法比較臺灣及日本的anti-ATLV陽性血清，結果顯示它們之間沒有差異。由此結果對ATLV可能由日本傳給臺灣加以討論。
• 英文摘要： For a seroepidemiologic study of adult T-cell leukemia virus (ATLV) infection in Taiwan, the gelatinparticle agglutination technique and the indirect immunofluorescence method were used for anti-ATLVtitration. Sporadic sero-positive cases were found all over the Taiwan districts except among the aborigines(0/947). Sero-positive rates ranged from 0 to 5.6% (except ATL family) and a total of 48 cases were foundin 3682 Han-Chinese. Among them 9 cases were newly found in family surveys, and 39 cases were observedin random samples. As an average positive rate was 1.0%, by calculation about 80,000 sero-positive casesare supposed to be present in Taiwan. A most remarkable feature of the sero-positive cases was the highrate in couples. Various patterns of sero-positive cases existed in pedigrees. Anti-ATLV positive sera ofChinese living in Taiwan and Japanese were compared by immunoprecipitation and there was no differencebetween them. The possible infection route from Japan to Taiwan is discussed.
• 中文關鍵字： ATl; ATLV; HTLV-I; Seroepidemiology; Sero-positive cases
• 英文關鍵字： --