- 作者: 曾琮欽 ; 杜采潓 ; 王義烽
- 作者服務機構: 高雄醫學院藥學系
- 中文摘要: Efficient procedures have been developed for the stereospecific synthesis of Angiotensin-converting enzyme inhibitor, Enalapril. The starting material,(R)-2-hydroxy-4-phenylbutyronitrile, is prepared from lipase-catalyzed acetylation. This process is useful for multigram-scale synthesis.
- 英文摘要: --
- 中文關鍵字: Enalapril; Ace Inhibitor; Enzymatical Synthesis; N-((S)-Ethoxycarbonyl-3-Phenylpropyl)-L-Alanyl-L-Proline
- 英文關鍵字: 酵素性合成