- 作者: Lee, C. J.; Chan, C. C.
- 作者服務機構: Department of Industrial Chemistry & Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan, Republic of China
- 中文摘要: --
- 英文摘要:
The need of prolonged heart surgery has prompted the development of
an efficient membrane-type oxygenator. The understanding of transport phenomena
and reaction kinetics involved in the system is a pre-requisite for the design of
such system. In this experimental study, we have utilized a single sheet silicone
rubber membrane mounted on a diffusion cell to investigate the mass transfer and
reaction kinetics of pig blood oxygenation.
From the experimental results, it was found that during the early stage of
oxygenation, the rate was determined by chemical absorption and could be
approximated with the following simple chemical kinetics:
Hb+O2→HbO2
Where, k=1. 25x 104 ml/mole-sec at 37℃ whereas, toward the final stage of
oxygenation, the rate is limited by the physical absorption mechanism. The overall
mass transfer coefficient (KA) ranges between 0.02 and 0.07 ml/sec depending on
the speed of agitation.
The overall mass transfer coefficient during the whole process of oxygenation is
proportional to 0.71 power of the rpm of stirrer; and is inversely proportional to
the degree of chemical saturation,
S=(ChbO2/Chb+Chb92)*100%
Although the overall rate of oxygenation is enhanced by the rpm of stirrer,
the increase in rpm appears to have a trade-off in that the degree of blood trauma
is more severe due to the effect of blood rheology. - 中文關鍵字: --
- 英文關鍵字: --