- 作者: 沈雅敬
- 作者服務機構: Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, R.O.C.
- 中文摘要: a-Amyrin margarate (1), moretenyl margarate (2) and moretenyl palmitate (3), three triterpenoid fatty acid esters, have been isolated from the acetone extract of the small twigs of Viburnum odoratissimum in addition to the three known compounds, a-amyrin palmitate (4), ursolic acid (7) and vibsanin-K (8). The structures of compounds 1-3 were elucidated based on extensive spectroscopic analysis and alkaline hydrolysis. Preliminary pharmacological studies revealed that vibsanin-K and ursolic acid exhibited significant cytotoxicity against human gastric (NUGC) and oral epidermoid (HONE-1) tumor cells at a concentration of 50 mg/mL while compounds 1-3 were inactive.
- 英文摘要: --
- 中文關鍵字: Viburnum odoratissimum; Triterpenoid fatty acid esters.
- 英文關鍵字: Viburnum odoratissimum; Triterpenoid fatty acid esters.