- 作者: 劉剛劍; 陳通保; 石慶雲
- 作者服務機構: Department of Pharmacy, National Defense Medical Center
- 中文摘要: By the addition of equivalent amount of appropriate amine on the carbon-carbon double bond of N-substituted maleamic acids under the influence of pyridine , a number of potential hypocholesteremics, N, N2-disubstituted DL-β-asparagines was prepared. For all N-alkyl- and N-arylmaleamic acids, the addition proceeded smoothly and resulted in satisfactory yields, but in the cases of N-heterocyclic analogs, transamidation was observed to occur simultaneously with the addition reactions.
- 英文摘要: --
- 中文關鍵字: --
- 英文關鍵字: --