- 作者: Anthony T. Tu
- 作者服務機構: Department of Biochemistry & Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, U.S.A
- 中文摘要:
The invention and subsequent use of laser as a light source in Raman spectroscopy ignited a wide application of Raman spectroscopy to organic compounds, biological compounds, and to biological tissues. Raman spectroscopy is a vibrational spectroscopy; Raman frequency is related to the mode of various vibrations in a molecule.
In this review article, the use of Raman spectroscopy on biological molecules done at A. T. Tu’s laboratory from 1962 to 1998, until his retirement, is summarized. The first part of the article is on peptide backbone structure and the local environment of amino acid residue side chain in proteins, mainly on snake neurotoxins. The second and third parts are direct analyses of gallstones and kidney stones by Raman spectroscopy without extraction, separation, and tedious chemical analysis. The last part is about the use of Raman spectroscopy to determine the anomeric bond in hexapyranosyl compounds. - 英文摘要: --
- 中文關鍵字: Raman spectroscopy; Biological compounds; Gallstones; Kidney stones; Proteins; Carbohydrate linkages
- 英文關鍵字: Raman spectroscopy; Biological compounds; Gallstones; Kidney stones; Proteins; Carbohydrate linkages