- 作者: 陳日榮、林儒緯、杜昌益、黃弘宜、陳益昇
- 作者服務機構: Institute of Pharmaceutical Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan 807, R.O.C.
- 中文摘要: Two new flavones, 8-hydroxy-7,3',4',5'-tetramethoxyflavone and 8,4'-dihydroxy-7,3',5'-trimethoxyflavone, together with thirteen known compounds have been isolated from the stem bark of Muntingia calabura. The structures of two new compounds were determined through spectral analyses. Among the isolates, 8-hydroxy-7,3',4',5'-tetramethoxyflavone, 8,4'-dihydroxy-7,3',5'-trimethoxyflavone, and 3-hydroxy-1-(3,5-dimethoxy-4-hydroxyphenyl)propan-1-one exhibited effective cytotoxicities (ED50 values = 3.56, 3.71, and 3.27 μg/mL, respectively) against the P-388 cell line in vitro.
- 英文摘要: --
- 中文關鍵字: Muntingia calabura; Tiliaceae; Stem bark; Flavones; 8-Hydroxy-7,3',4',5'-tetramethoxyflavone; 8,4'-Dihydroxy-7,3',5'-trimethoxyflavone; Cytotoxicity.
- 英文關鍵字: --