- 作者: 劉剛劍; 石慶雲
- 作者服務機構: Department of Pharmacy, National Defense Medical Center
- 中文摘要: A series of N-homocyclylcarbamoyl derivatives of maleamic acid and maleimide was prepared for hypocholesteremic and sulfhydryl-binding tests. The synthetic reactions involved in the controlled aminolysis of maleic anhydride with appropriate mono-substituted ureas and the resulting carbamoylmaleamic acids were then thermally dehydrated to the corresponding carbamoylmalemides. The mono-substituted ureas required in this synthesis were obtained by the action of amines on isocyanic acid produced in situ from nitrourea on heating in aqueous alcoholic solution.
- 英文摘要: --
- 中文關鍵字: --
- 英文關鍵字: --