- 作者: Perng-Haur Wang, Sheng-Jye Jou, Wen-Chuan Chen and Shoei-Sheng Lee*
- 作者服務機構: School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan, R.O.C.
- 中文摘要: A practical method for large-scale preparation of acid-labile aglycones including protopanaxadiol, protopanaxatriol, cycloastragenol, and jujubogenin from the corresponding glycoside containing fraction was developed. The key point of this improved method is to generate and maintain the critical reaction conditions, anhydrous and strongly basic, in situ. This effort over comes the weakness of the reported method for oxidative cleavage of glycones and scales up the preparation of these acid-labile aglycones for further studies.
- 英文摘要: --
- 中文關鍵字: Acid labile aglycones; Cycloastragenol; Jujubogenin; Oxidative cleavage; Strongly basic and anhydrous conditions; Large-scale preparation.
- 英文關鍵字: Acid labile aglycones; Cycloastragenol; Jujubogenin; Oxidative cleavage; Strongly basic and anhydrous conditions; Large-scale preparation.