• 作者： 吳香達；陳正益；魏如東；邱文隆
• 作者服務機構： 榮民總醫院婦?部; 國立陽明醫學院婦?科學系; 國立陽明醫學院生化學系
• 中文摘要： 從130位懷孕週數不同的孕婦，抽取羊水利用高液態層析法檢?完整性的卵燐質和神經燐質的比?。懷孕超過35週的116位孕婦比?除二位外，都高於10。胎兒出生後都?有呼吸窘迫症。相反地，低於35週的9位孕婦，七位比?少於10 的，出生後都有呼吸窘迫症；另外二位比?大於10的??有。 用這方法測定胎兒肺部成熟度，?簡單又可靠。往後在選擇性接生時，就可以預先知道胎兒?後生存的機會。尤其 是高危險懷孕，胎兒時常須要提早出生，而這種新生兒的死亡原因多半是呼吸窘迫。則羊水比?的測定，更具有臨床意義。
• 英文摘要： The total lecithin/sphingomyelin (L/S) ratio was measured by high-performance liquid chromatographic technique (HPLC) with 130 amniotic fluid (AF) samples from 130 pregnant women of variable gestational age. The L/S ratios of 116 cases, whose gestational weeks were at or above 35, were all but 2 above 10. They were all free from respiratory distress syndrome (RDS). The ratios of the other cases, whose gestational weeks were below 35, were all but 2 below 10. RDS occurred in 7 out of 9 but did not happen in those 2 cases whose L/S ratios were above 10. This newer method which provides a sensitive index of the functional development of the fetal lung and therefore of the ability to survive after birth when timing delivery, is of special value in the high risk pregnancy because premature delivery is often required and some neonatal deaths are due to RDS.
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