• 作者： Farghaly, A.M. ; Chaaban, I. ; El-Khawass, S.M. et al.
• 作者服務機構： Pharmaceutical Chemistry Dept., Alexandria Univ., Egypt
• 中文摘要： Six novel series of substituted thiazoline and thiazolidinone derivatives resulting from 2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-carbaldehyde and 1-phenyl-3-p-tolyl-1H-pyrazole-4-carbaldehyde were synthesized. The course of this synthesis included the preparation of two new series of disubstituted thiosemicarbazone precursors which were cyclized with phenacyl bromide, ethyl 2-chloroacetoacetate as well as ethyl bromoacetate to afford the target thiazolines and thiazolidinones. The antipyretic activity of some representative compounds was performed.
• 英文摘要： --
• 中文關鍵字： Antipyretic Agent; Pyrazole; Thiazoline; Thiazolidinone; Synthesis
• 英文關鍵字： 退熱劑；唑；唑；四氫唑；合成