- 作者: --
- 作者服務機構: Analytical Laboratory, BioFine Pharmaceuticals (Pvt.) Ltd., Multan, Pakistan
- 中文摘要: A rapid, simple and accurate spectrophotometric method is developed for the determination of ondansetron hydrochloride in pure and tablet formulations. The method depends on the charge-transfer complexation between ondansetron base as n-electron donor with chloranil as p-acceptor to give a colored complex, which absorbs maximally at 470 nm. Beer’s law is obeyed in the concentration ranges 70-980 μg mL-1 with molar absorptivity of 4.47 ’ 102 L mole-1 cm-1. The proposed method is precise, accurate and specific for the quantitative determination of drug in bulk and tablet formulations.
- 英文摘要: --
- 中文關鍵字: Spectrophotometry; Ondansetron hydrochloride; Dosage forms
- 英文關鍵字: --