- 作者: 陳柏成 ; 徐石 ; 楊定亞
- 作者服務機構: Department of Chemistry, Tunghai Christian University, Taiwan, R.O.C.
- 中文摘要: A general procedure for the synthesis of NG-alkyl, and NG-aryl-L-arginines with relatively high overall yield is reported. The key step involved the coupling of protected L-ornithine 4 with isothiourea 7 to give the fully protected NG-aryl-L-arginine derivative 8. Subsequent deprotection of 8 in acidic condition provided the final target compound 9 with an overall yield of more than 80%.
- 英文摘要: --
- 中文關鍵字: Nitric Oxide Synthase; Arginine; Citrulline; Inhibitor
- 英文關鍵字: 氧化氮合成;精胺酸;瓜胺酸;抑制劑