- 作者: 潘文彬,魏麗梅,魏麗蘭,吳志中,張芳榮,吳永昌
- 作者服務機構: Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, R.O.C.
- 中文摘要: Oxidation of a series of phenols with cerium(IV) ammonium nitrate (CAN) in acetonitrile under mild conditions yields the mixture of corresponding nitrophenols. In the cases of methylphenols and hydroxycarboxylic acids, the steric effect may reduce the nitration reaction. Compounds 3a and 4b showed selective activities to Hep 3B and Hep G2 cancer cell lines, respectively. Compound 2c showed selective activities to Hep G2 and MDA-MB-231 cancer cell lines. Furthermore, compound 10b showed selective activities to Hep G2, Hep 3B, MCF-7 and MDA-MB-231 cancer cell lines.
- 英文摘要: --
- 中文關鍵字: Cerium(IV) ammonium nitrate; Nitrophenols; Oxidative addition; Cytotoxicity.
- 英文關鍵字: --