- 作者: Abdel Hafez, Ali A. ; Awad, Ibrahim M.A. ; Ahmed, Ragaa A.
- 作者服務機構: Chemistry Dept., Faculty of Science, Assiut Univ., Assiut, Egypt
- 中文摘要: Some new azo sulfa drugs 3-cyano-4,6-diphenyl-1- [ 4-(N-substituted)sulfamyl ] phenylazo-2-pyridinone dyes and 3- cyano-4,6-diphenyl-1- [ 4-(N-substituted)sulfamyl ] phenylazo-2-pyridinethione dyes were synthesized by coupling of 4-(N-substituted) sulfamylbenzene diazonium salts with 3- cyano-4,6-diphenyl-2-pyridinone and/or with 3-cyano-4,6- diphenyl-2-pyridin-ethione. The corresponding iron, copper and mercury chelates were also prepared. All synthesized compounds were screened in vitro for antibacterial and antifungal activities.
- 英文摘要: --
- 中文關鍵字: Azo-Pyridinone(Thione)Drug; Metal Chelate; Biological Activity; Synthesis
- 英文關鍵字: 偶氮-啶酮(硫酮)藥物;金屬鉗合物;生物活性;合成