- 作者: Ru Ping Lee a,b, David Wang c, Nien Tsung Lin d, Yi Wei Chou e, Hsing I Chen a,f
- 作者服務機構: a Institute of Medical Sciences, b Department of Nursing, c Department of Medical Research, Cheng Hsin General Hospital, d Department of Microbiology, e Department of Public Health, f Department of Physiology, Tzu Chi University, Hualien, Taiwan, ROC
- 中文摘要: --
- 英文摘要: toring from femoral arterial catheterization. Accordingly,the modified unrestrained TCP measurement can beused in conscious rats as a noninvasive method.In physiological experiments, it is essential to measurearterial pressure (AP) and heart rate (HR) in animals. Tailcuff pressure (TCP) measurement using photoelectricvolume oscillometry has been commonly used. We de-signed a new technique for continuous measurement ofAP and HR in conscious, unrestrained rats. This is basedon the observation that fixation of the rat's tail with tapekeeps the animal in position without struggling. The ani-mal is free to move its body. To test the accuracy of thisnew technique, Sprague-Dawley rats underwent four APand HR measurement techniques. These included a newunrestrained method (UR) which was compared to thefollowing three methods: traditional restrained TCPmethod with restrainer, direct monitoring of AP and HRwith femoral artery catheterization and a combination ofphotoelectric volume oscillometry (with body heating to37 C) and femoral arterial recording. The results showthat the modified UR measurement provides accuratedata on AP and HR. This method obtains a lower value ofHR and similar mean AP when compared to direct moni-
- 中文關鍵字: --
- 英文關鍵字: Conscious state, Unrestrained condition, Arteria pressure, Heart rate, Noninvasive technique