- 作者: --
- 作者服務機構: Chemistry Department, Faculty of Science, Assiut University, Assiut, 71516, Egypt
- 中文摘要: Sodium salt of 4-hydroxy-6-methyl-2-phenylpyrimidine-5-carbonitrile (3) was subjected to alkylation with different a-halo compounds, where the corresponding O-alkylated products 4a-g were obtained. Ring closure of the O-alkylated product 4a-c performed using sodium ethoxide in refluxing ethanol afforded furo[2,3-d]pyrimidines 5a-c. The latter compounds on reaction with a variety of reagents gave other new furopyrimidines as well as a number of furodipyrimidines.
- 英文摘要: --
- 中文關鍵字: Furopyrimidines; Pyrimidofuropyrimidines; Synthesis; Biological activity.
- 英文關鍵字: --