- 作者: --
- 作者服務機構: Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran
- 中文摘要: A kinetic method for the accurate and sensitive determination of metronidazole benzoate (MB) has been described. The method is based on the oxidation of MB with KMnO4 in alkaline medium in the presence of sodium dodecyl sulphate (SDS). At a fixed time of 10 min, the formed magnate ion is spectrophotometrically measured at 610 nm. The determination of MB by the fixed-concentration and rate constant method is feasible with the calibration equation obtained, but the fixed-time method proves to be more applicable. The proposed method was successfully used for the quantitative determination of MB in suspended oral syrup after the separation of MB with a simple separation method. Beer’s law was obeyed from 0.55 mgL-1 to 33 mgL-1 and the RSD% value for syrup was 3.44. The results obtained agreed with those obtained by the BP method.
- 英文摘要: --
- 中文關鍵字: Metronidazole benzoate determination; Kinetic-Spectrophotometry; KMnO4; SDS.
- 英文關鍵字: --