- 作者: 蔡厚仁,謝紀偉
- 作者服務機構: Department of Applied Chemistry, Chung Cheng Institute of Technology, National Defense University, Tahsi, Taoyuan 335, Taiwan, R.O.C.
- 中文摘要: Addition of trimethylsilyl trifluoroacetate to the carbanions of a-fluorobenzyl-phosphonate (3) or diisopropyl(fluorocarbethoxymethyl)phosphonate (9) formed the corresponding intermediates [CF3C(O)CFPh]-Li+ (10) and [CF3C(O)CFCO2Et]-Li+ (11), respectively. Subsequent protonation, alkylation or allylation of 10 and 11 afforded trifluoromethyl fluorobenzyl ketones 12 and ethyl 2,4,4,4-tetrafluoroacetoacetates 13. Based on the results obtained, a plausible mechanism was proposed.
- 英文摘要: --
- 中文關鍵字: Michaelis-Arbuzov reaction; Wittig-Horner reaction; Protonation; Alkylation; Allylation.
- 英文關鍵字: --