- 作者: 魏國佐
- 作者服務機構: Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi 621, Taiwan
- 中文摘要: The assembly strategy to prepare a monolayer of bovine serum albumin on the surface of silica gel supported gold nanoparticles is described. The stereo-specific recognition ability of this material was evaluated by enantioresolution of Dansyl-norvaline. For enantiomeric separation, the influences of buffer concentration and the concentration of organic modifier on the separation performance were investigated. A better separation in terms of enantioresolution and peak shape was found with the phosphate concentration at 30 mM. Moreover, the peak shape and resolution can be improved by the addition of methanol solution. Enantioresolution of Dansyl-norvaline was obtained from this material at optimized conditions. It appears that the immobilization of a monolayer of bovine serum albumin on gold nanoparticles as the chiral selector of Dansyl-derivative amino acid is promising.
- 英文摘要: --
- 中文關鍵字: Bovine serum albumin; Gold nanoparticles; Enantiomeric separation; Dansyl-derivative amino acid.
- 英文關鍵字: --