- 作者: 莊中南 ; 莊麗紋 ; 葉名倉
- 作者服務機構: 台灣師範大學化學系
- 中文摘要: Reaction of lithium diisopropylamide (LDA) with(.eta./sup 4/-1,3-cyclohexadiene)Fe(CO)/sub 3/ complexes bearing functionalized side chains at C-5, under an atmosphere of carbon monoxide, gives bridged bicyclo [ 3.2.1 ] octene and bicyclo [ 3.3.1 ] nonene systems after electrophilic quenching. Under the same reaction conditions, intramolecular cyclization of acyclic(.eta./sup 4/-1,3-butadiene)Fe(CO)/sub 3/ complexes with functionalized side chains at the terminal position of the diene ligands furnishes fused bicyclo [ 3.3.0 ] octanone and bicyclo [ 4.3.0 ] nonanone derivatives after acid quenching. The addition of a variety of the highly functionalized zinc- copper reagents RCu(CN)ZnI to the (.eta./sup 7/- cycloheptatrienyl)Cr(CO)/sub 3/ gives (.eta./sup 6/- cyclohepta-1,3,5-triene)Cr(CO)/sub 3/ complexes with a functionalized side-chain at the C-7 position of the ring. Intramolecular cyclization of ester-substituted adducts using lithium diisopropylamide generates fused bicyclo [ 5. 3.0 ] decane and bicyclo [ 5.4.0 ] undecane derivatives. The addition of a variety of the highly functionalized zinc-copper reagents RCu(CN)ZnI to the(.eta./sup 4/-cyclohexa-1,3-diene)Mo(CO)/sub 2/(Cp) at the terminus of the coordinated diene ligand gives [ Mo(.pi.- allyl)(CO)/sub 2/(Cp) ] (Cp=cyclopentadienyl) complexes with the functionalized side-chain at the C-4 position of the ring. Intramolecular cyclization of the (.pi.-allyl) molybdenum complex containing a pendant propanoic acid unit generates the .delta.-lactone derivative.
- 英文摘要: --
- 中文關鍵字: Functionalized Zinc-Copper Reagent; Intramolecular Cyclization; Organic Synthesis; Functionalization
- 英文關鍵字: 官能化鋅-銅試劑;分子內環化;有機合成;官能化