- 作者: --
- 作者服務機構: Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt
- 中文摘要: The reaction of the aminopyrazole 1 with benzenesulfonyl chloride, arenediazonium salt, chloroacetyl chloride, ethoxy methyleneamlononitrile and with ethyl 2-cyano-3-ethoxyacrylate gave the substituted 3-methyl-1-phenylpyrazole 2-5a,b. Compound 5b was cyclized to 6 and to 7 by treating it with AlCl3 and with POCl3, respectively. Compound 6 converted to 7 by boiling it in POCl3/PCl5. Compound 10b was produced through reaction of 9 with acetophenone. Reaction of 1 with benzylidinemalononitrile afforded 11. New methods for preparation of 15 and 16 are described. The reaction of 8 with malononitrile, thiosemicarbazide, phenyl hydrazine and acetophenone afforded compounds 18-21. The reaction of 21 with malononitrile gave 22. Compounds 23-26 were produced upon reaction of 10a with malononitrile, phenyl hydrazine, thiosemicarbazide, semicarbazide and with benzaldehyde, respectively.
- 英文摘要: --
- 中文關鍵字: Pyrazole; Pyrazolo[3,4-b]pyridine.
- 英文關鍵字: --