- 作者: --
- 作者服務機構: Synthetic Organic Chemistry Laboratory, Department of Chemistry, Dr. H. S. Gour University, Sagar (M.P.) 470 003, India
- 中文摘要: Arylidenes of thiazolidines with mercaptobenzoxazole, namely[(aryl-4-oxo-1,3-thiazolidin)-hydrazinoacetyl-mercaptobenxazole]; (5-arylidene)-2-aryl-4-oxo-1,3-thiazoliden hydrazinoacetyl-mercaptobenxazole were synthesized. Their chemical structures have been confirmed by 1H NMR, IR, mass spectra and also by microanalytical data. Antimicrobial evaluation was done by agar dilution method against three pathogenic bacteria viz. Bacillus subtilis, Escherichia coli and Klebsiella pneumoniae and three pathogenic fungi viz. Aspergillus niger, Candida albicans and Fusarium oxysporum. Among new derivatives evaluated, the chloro derivatives exhibited higher potency as compared to the standard drugs streptomycin (for bacteria) and griseofulvin (for fungi) against the tested organisms.
- 英文摘要: --
- 中文關鍵字: Thiazolidines; Mercaptobenzoxazole; Antimicrobial agent.
- 英文關鍵字: --