- 作者: 沈清良; 丁文華; 張正廣
- 作者服務機構: 國立成功大學醫學院解剖學科; 中國醫藥學院神經內科
- 中文摘要:
本研究以免疫組織化學法來研究甲苯對大白鼠下丘腦中的某些激素分泌神經元和含某些神經傳遞物的神經纖維的影
響。本實驗經多次腹腔注射總量為7.5m1的甲苯後,發現下丘腦內的血管加壓素神經元、催產激素神經元、和神經?
Y神經元有顯著減少的情形。而且發現在正中隆起的血管加壓素性、催產激素性、正腎上腺素性及神經?Y性的神經
纖維的密度有減少的現象。但促進黃體生成促激素的神經元則無影響。
i - 英文摘要: The effect of toluene on the hypothalamic hormone-secreting neurons and neurotransmitter-containingfibers in the rat was investigated by immunohistochemical methods. Multiple intraperitoneal injections oftoluene (totally 7.5 ml) led to significant decreases of the neuronal numbers of vasopressin, oxytocin andneuropeptide Y in the preoptic and hypothalamic areas. The densities of vasopressin, oxytocin, norepine-phrine and neuropeptide Y immunoreactive fibers of the toluene dose group decreased markedly in themedian eminence. In contrast, LHRH neurons remained unchanged.
- 中文關鍵字: toluene; hypothalamus; immunohistochemistry.
- 英文關鍵字: --