- 作者: 阿特拉阿默得,吳明軒,吳永昌,戴昌鳳,許志宏
- 作者服務機構: Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, R.O.C.
- 中文摘要: The metabolites, (24S)-3b-acetoxyergost-5-en-21-oic acid (2), 5¢-O-acetylthymidine (3), 3¢-O-acetylthymidine (4), and p-vinylbenzyl alcohol (5), along with a known steroid (1) were isolated from the EtOAc extract of the Formosan soft coral Caldiella australis. The structures of new metabolites were determined on the basis of spectroscopic (including 1D and 2D NMR) analyses and by comparison of their NMR spectral data with those of related compounds. Except for 3, all compounds exhibited cytotoxic activity of various degrees of potency against a limited panel of human liver and breast cancer cell lines.
- 英文摘要: --
- 中文關鍵字: Cladiella australis; Steroids; 5¢-O-acetylthymidine; 3¢-O-acetylthymidine; p-Vinylbenzyl alcohol; Cytotoxicity; Soft coral.
- 英文關鍵字: --