• 作者： 彭芳谷；戚謹文；曹桂蘭
• 作者服務機構： 榮民總醫院外科部一般外科
• 中文摘要： 本實驗測定了乳癌、胃癌、食道癌、肺癌、肝癌、胰?癌、大腸癌及直腸癌患者286人之血清中5'-核?酸?及 Sialyltransferase之活性，將?活性與正常者比較時，發現肝癌及胰?癌患者之?活性與正常者有顯著差異，外科手 術對於5'—核?酸?活性?有影響。可是在Sialyltransferase活性方面，外科手術與其活性之改變有關連性。短期追 蹤癌症患者時，發現?活性成不規則之起伏，長期之結果則有待進一?之追蹤及研究。
• 英文摘要： Serum sialyltransferase and 5'-nucleotidase activities were determined in 286 Chinese patients with cancers of breast, stomach, esophagus, lung, liver, pancreas, colon, and rectum. The enzyme levels were compared to that of normal, and significant differences were found in the hepatoma and pancreatic cancer group. Surgical operations showed no significant effect on the 5'-nucleotidase levels. However, a good correlation was found in the sialyltransferase activity before and after operation. Serial follow-up of patients showed that enzyme levels fluctuated in short term period. The long term effect of tumor burden on enzyme levels needs further investigation.
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