- 作者: --
- 作者服務機構: Chemistry Department, Faculty of Science, Cairo University, Faiyoum 63514, Egypt
- 中文摘要: Heterocyclization of bis(2-oxo-indol-3-ylidene)-galactaric acid hydrazide (3) with a variety of one-nitrogen cyclizing agents gave the corresponding 1,4-bis{1,2,4-triazino[5,6-b]indol-3-yl}-galacto-tetritols 4-8. Acetylation of the latter double headed acyclo C-nucleosides with acetic anhydride in the presence of pyridine at ambient temperature resulted in N- and O-acetylation to give the corresponding 1,2,3,4-tetra-O-acetyl-1,4-bis{1,2,4-triazino[5,6-b]indol-3-yl}-galacto-tetritols 9-13 which were found to exist in centrosymmetric zigzag conformations 20. The assigned structures were corroborated by 1H, 13C NMR as well as mass spectra.
- 英文摘要: --
- 中文關鍵字: Bis(2-oxo-indol-3-ylidene)-galactaric acid hydrazide; One-nitrogen cyclizing agents; Heterocyclization; Double headed 1,2,4-triazino[5,6-b]indole acyclo C-nucleosides.
- 英文關鍵字: --