- 作者: 梁曉天
- 作者服務機構: 北京巿中國醫學科學院藥物研究所
- 中文摘要: This review describes our preliminary results of ring enlargement of N-heterocycles by N-ylide formation at a targeted site. Before development of this method, the strategy can be traced to our modified Hofmann degradation led at first to several miscarried probings on the reaction between N-halomethyl ammonium salts and halophilic reagents.
- 英文摘要: --
- 中文關鍵字: Ring Enlargement; Ylide; Heterocycle; Halophilic Reagent; Hofmann Degradation
- 英文關鍵字: 環擴大反應;亞烷基;雜環;親鹵性試劑;何夫曼降解