• 作者： 沈清良
• 作者服務機構： 國立成功大學醫學院解剖科
• 中文摘要： 本實驗是以免疫組織化學法來研究神經胜? Y 在大白鼠前腦的分佈。抗體的專一性之試驗是將神經胜? Y 抗體與抗
  原先混合後，再將組織釀培於混合液中，而不引起任何染色反應而定。本實驗之結果發現含神經胜? Y 的神經元廣泛的
  分佈於前腦中。這些區域包括大腦新皮質、大腦底部構造、膈區、終末線條核、新線條體，丘腦下部弓狀核和背側及腹
  膝狀體之間。本研究也發現含神經胜? Y 的纖維廣泛的分佈於前腦中。例如視前區、丘腦下部及丘腦室傍核。本文中亦
  討論到神經胜? Y 與鳥類胰臟多胜之分佈之比較。且亦略提及神經胜? Y 的可能之功能。了
• 英文摘要： The distribution of neuropeptide Y (NPY) like immunoreactivity was investigated in the forebrain ofthe rat with immunohistochemical methods. Specificity of the antisera was established by the absence ofall immunoreactive staining in tissue incubated in antisera which had been preabsorbed with the pure NPYantigen. NPY containing cells were distributed widely in the forebrain. These included neocortex, basalforebrain, septum, bed nucleus of the stria terminalis, neostratium, hypothalamic arcuate nucleus, andintergeniculate leaflet. This study also demonstrated an extensive network of NPY fibers in various areasof the forebrain such as the prepotic area, the hypothalamus and the paraventricular nucleus of the thala-mus. The distribution of avian pancreatic polypeptide and NPY was compared, and the possible impor-tance of NPY is briefly discussed.
• 中文關鍵字： rat; immunohistochemistry; forebrain; neuropeptide Y
• 英文關鍵字： --