- 作者: Mei-Chih Lina , Kuang-Chao Wangb and Shoei-Sheng Leeb
- 中文摘要:
aNational Laboratories of Food and Drugs, Department of Health, Executive Yuan, R.O.C.
bSchool of Pharmacy, National Taiwan University, Taipei 100, Taiwan, R.O.C.
Fractions major in ginsenosides Rg1 and Rb1 from Sanchi saponins were transformed by human fecal flora. This study yielded the corresponding aglycone, protopanaxatriol, in 49.4% from Rg1, protopanaxadiol 20-O-glucoside in 54.8% from Rb1, and dihydroprotopanaxadiol 20-O-glucoside in 87.6% from dihydro Rb1, by incubation with healthy feces for 70 h in subgram level. Nevertheless large-scale incubation of crude Sanchi saponins revealed the complete biotransformation of Rb1 and the almost unchanged Rg1. A small amount of Rg1 was found to be converted into 20R-ginsenoside Rh1 and its dehydration product, 20(22)Z-ginsenoside Rh4. - 英文摘要: --
- 中文關鍵字: --
- 英文關鍵字: --