- 作者: 畢萬邦
- 作者服務機構: 國立臺灣大學
- 中文摘要: Parabiotic rate have been used to study the secretory capability of pituitarygland on growth hormone. Sprague-Dawley strain rats were used to make parabiotictriplets between 28 and 35 day old. One and two weeks later, two lateral partnersof the parabioants were hypophysectomized. Some of them were served as parabioticcontrols. A few of their littermates with a sham parabiotic operation were takenas single controls. During experimental period, one half of the parabioants wereprovided food and water ad libitium and the others their food intake was controlledunder forced feeding. Nose-occipital length were measured once every 10 to 14 days. Forty days later,their individual body weight, weight of endocrine glands, tibia length were recordedand pictures were taken, too. Concerning the gain of noseoccipital length, the growthrate of intact partner of parabiotic triplets was in a same rate as parabiotic controlsand single controls, although the body weight of intact partner was less thanthat of single controls; on the other hand, hypophysectomized partner only grewa 42.4% in nose-occipital length and 65.4% in body weight of their intact partners.These results suggested that the pituitary gland of parabiotic intact partner hada potential supply of growth hormone for combination of itself and its hypophy-sectomized partners.
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