- 作者: Tien-Chu Chang and Chinpiao Chen*
- 作者服務機構: Department of Chemistry, National Dong Hwa University, Soufeng, Hualien 974, Taiwan, R.O.C.
- 中文摘要: Chiral (5-aryl-10,10-dimethyl-6-aza-tricyclo[7.1.1.02,7]undeca-2(7),3,5-trien-8-yl)-diphenyl-methanols were prepared from highly enantiopure (1R)-(+)-α-pinene (> 97% ee), and applied in the enantioselective addition of diethylzinc to substituted benzaldehydes, to yield alcohols with the (S)-configuration with an enantiomeric excess that typically ranges from 19 to 86%. Importantly, the electron-withdrawing substituents at the meta-position of the substituted benzaldehydes exhibited high enantioselectivity during alkylation using diethylzinc.
- 英文摘要: --
- 中文關鍵字: Enantioselective catalysts; Diethylzinc; Benzaldehyde; Hammett substituent constants.
- 英文關鍵字: --