• 作者： 鍾來如; 楊吉雄; 黃天賜; 薛樹清; 余英敏
• 作者服務機構： 榮民總醫院內科部; 國防醫學院內科學系; 陸軍八○三總醫院內科
• 中文摘要： 木報告以榮民總醫院慢性骨髓性白血病 120 例為研究對象，分析其症狀發生及診斷疾病之月份時間，再歸入各有關之季節。每年之2、3、4月份為春季，5、6、7月份為夏季等，以下類推，以便察知有否特殊之季節發生率。其結果顯示：夏季症狀發生率最多，約佔全部之 35.8%(p＜0.05)。其他季節之症狀發生率及各季節之診斷率在統計學上無意義。 不少感染性疾病有其週期性及季節性乃公認之事實。唯白血病迄未有明確證據顯示與病毒或細菌傳染有關。本報告顯示夏季症狀發生率頗高。在夏季，人體之基礎代謝率增加，其他如內分泌、體內其他功能調節異常等因素，可能是本報告結果之較佳解釋。
• 英文摘要： One hundred and twenty cases of chronicmyelogenous leukemia (CML) diagnosed andtreated at Taipei Veterans General Hospital wereanalysed for the seasonal onset of the symptomsand the season of the disease diagnosed. Theseasonal prevalence was determined by groupingthese cases into their corresponding seasons, i.e.spring (February, March and April), summer(May, June and July), autumn (August, Septem-ber and October) and winter (November, De-cember and January) according to Chinese lunarcalendar. The results showed that about 35.8%of CML cases had their symptoms onset in thesummer season (p＜0.05). The symptomaticoccurrence of the disease in the other seasonsand the time of the disease diagnosed in indi-vidual seasons were not statistically significant. It is well documented that seasonality isa striking feature in many infectious diseases.Whether leukemia correlated with viral or bac-terial infection is still in controversy. Theresults showed a significant increase in prevalenceof the symptoms of CML in summer season.The increase of basal metabolic rate accompaniedwith other factors, e.g. endocrinic or other in-ternal organic dysfunctions, might be the mostsuitable explanation.
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