- 作者: Steven Ting-Yu Chuo, Jasper Che-Yung Chien and Charles Pin-Kuang Lai
- 作者服務機構: 1. Institute of Atomic and Molecular Sciences, Academia Sinica, No. 1, Roosevelt Rd., Sec. 4, Taipei 10617, Taiwan 2. Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei, Taiwan
- 中文摘要:
- 英文摘要:
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They range from 30 nm to several micrometers in diameter, and ferry biological cargos such as proteins, lipids, RNAs and DNAs for local and distant intercellular communications. EVs have since been found to play a role in development, as well as in diseases including cancers. To elucidate the roles of EVs, researchers have established different methods to visualize and study their spatiotemporal properties. However, since EV are nanometer-sized, imaging them demands a full understanding of each labeling strategy to ensure accurate monitoring. This review covers current and emerging strategies for EV imaging for prospective studies. - 中文關鍵字:
- 英文關鍵字: Extracellular vesicles exosomes, Microvesicles, Imaging, Biodistribution, Fluorescence, Bioluminescence, MRI, SPECT, Dyes